Molekulare Basis sensorischer Biologie

Kickoff and Fare Well Meeting 2016

Scientific Kick-Off Meeting of the RTG "Molecular Basis of Sensory Biology" (DFG-GK  1885)

02.-04.10.2016 at the HWK Delmenhorst

Meeting for all members of the RTG Sensorybio

- Exchange of information

- New ideas

- Getting to know each other

Invited Speaker: Keynote Lecture: U.B. Kaupp (Forschungszentrum Caesar, Bonn)

                         R. Seifert (Medizinische Hochschule Hannover)

                         E.M. Neuhaus (Universitätsklinikum Jena)

 

programme

 

 

 

Kick-Off Meeting 2013

Scientific Kick-Off Meeting of the RTG "Molecular Basis of Sensory Biology" (DFG-GK  1885)

 

9.00

Welcome –Speaker of the RTG Prof. KW Koch & Prof. H. Mouritsen

9.15

Keynote-Lecture: Prof. Dr. P. Hore (Oxford)
Animal navigation using magnetically sensitive chemistry

 

Coffee Break

11.00

Project Presentation of PhD students

 

J. Leyk: Stress responses and cell death mechanisms leading to sensory dysfunction

 

A. Einwich: The role of cryptochromes in magnetoreception

 

S. Sulmann: Conformational changes in multiprotein complexes operating in sensory transduction

 

M. Trinkler: “Aromatoleum aromaticum”: Sensory distinction of structurally similar aromatic compounds

 

J. Robin: Ultrafast Dynamics of Molecular Mechanisms in Sensory Systems

 

J. Segelken: Modulation of electrical synapses: involvement of phosphorylation systems and scaffolding proteins in connexin-turnover and trafficking in horizontal cell networks of the vertebrate retina 

13.00

Lunch

14.30

Lecture Daniele Dell´Orco (Verona)
Changing paradigms in the sensory world

15.45

RTG Organization: Finances, Lecture Series, Summer School

16.15

Fare well Coffee

 

 

 

Keynote Lecture

Prof.  Peter Hore, Department of Chemistry, University of Oxford, UK

Animal navigation using magnetically sensitive chemistry

Migratory birds travel spectacular distances each year, navigating and orienting by a variety of means, most of which are poorly understood. Among them is a remarkable ability to perceive the intensity and direction of the Earth’s magnetic field. Biologically credible mechanisms for the sensing of such weak fields are scarce and in recent years just two proposals have emerged as frontrunners. One, essentially classical, involves clusters of iron-containing particles. The other relies on the magnetic sensitivity of short-lived photochemical intermediates called radical pairs. The latter model began to attract interest following the proposal that the necessary photochemistry could take place in the bird’s retina in specialised photoactive proteins called cryptochromes. The coherent dynamics of the electron-nuclear spin systems of pairs of organic radicals is conjectured to lead to changes in the yields of reaction products even though the interaction with the geomagnetic field is more than six orders of magnitude smaller than the thermal energy per molecule.

In this talk, I will outline the basis of the radical pair mechanism, present some of the experimental evidence for the cryptochrome hypothesis and comment on the extent to which cryptochromes are fit-for-purpose as magnetoreceptors.