Molecular Neurobiology

Projects

  • The biochemical characterization and analysis of the functional role of the cytoskeleton and cytoskeleton-associated proteins in oligodendrocytes.

  • Heat shock proteins as inhibitors of Tau aggregation in oligodendrocytes.
  • Protein aggregate formation in oligodendrocytes: dysregulation of tau and neural degeneration.
  • The role of membrane lipid composition in regulating stress responses and cell survival in brain cells.

  • Oxidative stress in oligodendrocytes and demyelinating disorders: the role of stress proteins and mitochondrial impairment in health and disease.

  • The establishment of neural cell cultures as model systems for pharmacological and toxicological analyses.

  • Protein quality control systems during neurodegeneration and aging.

 

Our group is supported by