Medical Physics

Auditory Neurosensory Science

This group gathers several research projects and PIs in noninvasive auditory neuroscience. Our research aims at finding neural correlates of psychoacoustic performance in human listeners. Our goal is to understand how sound pressure entering the ears leads to a representation of what we hear, and how sound is represented along the ascending auditory pathway and cortex.

Our research covers topics on sound localisation, loudness, modulation, pitch perception, and sound representation in normal, hearing impaired, and cochlear implant listeners. Our methods include psychophysics, otoacoustic emssions (OAE), electroencephalography (EEG), and functional MR imaging (fMRI) of the human auditory system.

Principal Investigators

Prof. Dr. Sarah Verhulst
Physiology and Modeling of Auditory Perception; Interdisciplinary approaches studying sound encoding along the auditory pathway combining OAE, EEG, psychoacoustics and computational models.
» Team website

PD Dr. Stefan Uppenkamp
Functional measures of the human auditory system; interrelation of psychophysical performance and activation maps as determined by functional MRI and MEG. 
» Team Website

Dr. Manfred Mauermann
Otoacoustic emissions, cochlear mechanics, and their relation to psychoacoustics.
» Team Website

Dr. Mathias Dietz
ABCIT Project (Advancing Binaural Cochlear Implant Technology); Research topics are focused at understanding, modelling, and improving binaural hearing. Experimental methods include EEG and psychoacoustics with both normal hearing and cochlear implant subjects.
»Team Website

Recent Publications

JOURNAL ARTICLES

Verhulst S, Bharadwaj H, Mehraei G, Shera CA, Shinn-Cunningham BG (accepted). Functional modeling of the human auditory brainstem response to broadband stimulation. Journal of the Acoustical Society of America.

Bharadwaj H, Masud S, Mehraei G, Verhulst S, Shinn-Cunningham B (2015). Individual differences reveal correlates of hidden hearing deficits. Journal of Neuroscience 35 (5): 2161-2172.

Dietz M., Klein-Hennig M., Hohmann V. (2015). The influence of pause, attack, and decay duration of the ongoing envelope on sound lateralization. J. Acoust. Soc. Am. 137, EL137-EL143.

Hansen R., Santurette S., Verhulst S. (2014). Effects of spontaneous otoacoustic emissions on pure-tone frequency difference limens. Journal of the Acoustical Society of America, 136, 3147- 58.

Altoè A., Pulkki V., Verhulst S. (2014). Transmission-line Cochlear Models: Improved Accuracy and Efficiency. Journal of the Acoustical Society of America – 136 EL302.

Dietz, M., T. Marquardt, A. Stange, M. Pecka, B. Grothe, D. McAlpine (2014). Emphasis of spatial cues in the temporal fine structure during the rising segments of amplitude-modulated sounds II: Single Neuron Recordings. J. Neurophysiol. 111, 1973-1985.

Uppenkamp, S., M. Röhl (2014). Human auditory neuroimaging of intensity and loudness. Hearing Research 307, 65-73.

Bharadwaj, H.M., Verhulst S., Shaheen L., M.C. Liberman, Shinn-Cunningham, B.G. (2014). Cochlear Neuropathy and the coding of supra-threshold sound. Front. Sys. Neurosci. 8, 26 (18 pages)

Bach, J.P., M. Lüpke, P. Dziallas, P. Wefstaedt, S. Uppenkamp, H. Seifert, I. Nolte (2013). Functional magnetic resonance imaging of the ascending stages of the auditory system in dogs, BMC Veterinary Research 9, 210 (10 pages).

Bianchi, F., Verhulst, S., Dau,T. (2013). Experimental evidence for a cochlear source of the precedence effect. J. Assoc. Res. Otolaryngol. 14(5), 767-779.

Dietz, M., T. Marquardt, N.H. Salminen, D. McAlpine (2013). Emphasis of spatial cues in the temporal fine structure during the rising segments of amplitude-modulated sounds. Proc. Natl. Acad. Sci. 110, 15151-15156.

Dietz, M., L.R. Bernstein, C. Trahiotis, S.D. Ewert, V. Hohmann (2013). The effect of overall level on sensitivity to interaural differences of time and level at high frequencies. J. Acoust. Soc. Am. 134, 494-502.

Dietz, M., T. Wendt, S.D. Ewert, B. Laback, V. Hohmann (2013). Comparing the effect of pause duration on threshold interaural time differences between exponential and squared-sine envelopes. J. Acoust. Soc. Am. 133, 1-4.

Puschmann, S., J. Özyurt, S. Uppenkamp, C.M. Thiel (2013). Pitch-induced responses in right auditory cortex correlate with musical ability in normal listeners. Neuroreport 24, 841-845.

Klein-Hennig, M., Dietz M., Klinge-Strahl, A., Klump, G.M., Hohmann, V. (2012). Effect of mistuning on the detection of a tone tasked by a harmonic tone tomplex. PLoS ONE 7(11), e48419.

Röhl, M., Uppenkamp, S. (2012). Neural coding of sound intensity and loudness in the human auditory system. J. Assoc. Res. Otolaryngol. 13, 369-379.

Verhulst, S., T. Dau, C.A. Shera (2012). Nonlinear time-domain cochlear model for transient stimulation and human otoacoustic emission. J. Acoust. Soc. Am. 132(6), 3842-3848.

Dietz, M., Ewert, S.D., Hohmann, V. (2012). Lateralization based on interaural differences in the second-order amplitude modulator. J. Acoust. Soc. Am. 131, 398-408

Dietz, M., S.D. Ewert, V. Hohmann (2011). Auditory model based direction estimation of concurrent speakers from binaural signals. Speech Commun. 53, 592-605.

Gutschalk, A., S. Uppenkamp (2011). Sustained responses for pitch and vowels map to similar sites in human auditory cortex. Neuroimage 56, 1578-1587.

Klein-Hennig, M., Dietz, M., V. Hohmann, S.D. Ewert (2011). The influence of different segments of the ongoing envelope on sensitivity to interaural time delays. J. Acoust. Soc. Am. 129, 3856-3872.

Röhl, M., B. Kollmeier, S. Uppenkamp (2011). Spectral loudness summation takes place in the primary auditory cortex. Hum. Brain Mapp. 32, 1483-1496.

Verhulst, S., J.M. Harte, T. Dau (2011). Temporal suppression of the click-evoked emission level-curve. J. Acoust. Soc. Am. 129(3), 1452-1463. 

Epp, B., Verhey, J. L., Mauermann, M., (2010) Modeling cochlear dynamics: Interrelation between cochlea mechanics and psychoacoustics, J Acoust Soc Am, 128, 1870-1883.

BOOK CHAPTERS

Spille, C., Meyer, T., Dietz, M., Hohmann, V. (2013). Binaural Scene Analysis with Multidimensional Statistical Filters. In “The technology of binaural listening”. J Blauert Ed., pp. 145-170. New York: Springer.

Dietz, M., Marquardt, T., Greenberg, D., McAlpine, D. (2013). The influence of the envelope waveform on binaural tuning of neurons in the inferior colliculus and its relation to binaural perception. In Moore, B.C.J., R.D. Patterson, I. Winter, R.P. Carlyon, H.E. Gockel (Eds.), Basic Aspects of Hearing: Physiology and Perception - 16th International Symposium on Hearing, pp. 223-230. New York: Springer.

Uppenkamp, S., C.H. Uhlig, J.L. Verhey (2013) Cortical representation of the combination of monaural and binaural unmasking. in Moore, B.C.J., R.D. Patterson, I. Winter, R.P. Carlyon, H.E. Gockel (Eds.), Basic Aspects of Hearing: Physiology and Perception - 16th International Symposium on Hearing, pp. 435-442. New York: Springer.

Verhulst, S., Bianchi, F. and Dau, T. (2013). Cochlear contributions to the precedence effect. In: Moore, B.C.J., R.D. Patterson, I. Winter, R.P. Carlyon, H.E. Gockel (Eds.), Basic Aspects of Hearing: Physiology and Perception - 16th International Symposium on Hearing, pp. 283-291. New York: Springer.

PEER-REVIEWED CONFERENCE ARTICLES

Verhulst S. and Shera C.A. (in press). Relating the Variability of Tone-burst Otoacoustic Emission and Auditory Brainstem Response Latencies to the Underlying Cochlear Mechanics. 12th Mechanics of Hearing Workshop.

Saremi A., Stenfelt S., Verhulst S. (in press). How Do the Medial Olivocochlear Efferents Influence the Biomechanics of the Outer Hair Cells and thereby the Cochlear Amplifier? Simulation Results. 12th Mechanics of Hearing Workshop.

Hu, H., Ewert, S. D., Campbell, T., Kollmeier, B., Dietz, M. (2014).  An interaural electrode pairing clinical research system for bilateral cochlear implants, in 2nd IEEE China SIP (in press)

Spille, C., Dietz, M., Hohmann, V., Meyer, B. (2013). Using binaural processing for automatic speech recognition in multi-talker scenes, in 38th International Conference on Acoustics, Speech, and Signal Processing (ICASSP), pp. 7805-7809

Verhulst, S., Shera, C.A., Harte J.M. and Dau, T. (2011). Can a static nonlinearity account for the dynamics of otoacoustic emission suppression? In: Shera, C.A. and Olson, E.S. (Eds.) What fire is in mine ears: progress in auditory biomechanics, AIP, 257 – 263.