Neurobiologie

Aktuelle Publikationen

2015

Dorgau B, Herrling R, Schultz K, Greb H, Segelken J, Ströh S, Bolte P, Weiler R, Dedek K, Janssen-Bienhold U. Connexin50 couples axon terminals of mouse horizontal cells by homotypic gap junctions. DOI: 10.1002/cne.23779. [Epub ahead of print]

Lee SC, Meyer A, Schubert T, Hüser L, Dedek K, Haverkamp S. Morphology and connectivity of the small bistratified A8 amacrine cell in the mouse retina. DOI: 10.1002/cne.23752. [Epub ahead of print]

2014

Brüggen B, Meyer A, Boven F, Weiler R, Dedek K. Type 2 wide-field amacrine cells in TH::GFP mice show a homogenous synapse distribution and contact small ganglion cells. Eur J Neurosci 41, 734-747.

Arango-Gonzalez B, Trifunović D, Sahaboglu A, Kranz K, Michalakis S, Farinelli P, Koch S, Koch F, Cottet S, Janssen-Bienhold U, Dedek K, Biel M, Zrenner E, Euler T, Ekström P, Ueffing M, Paquet-Durand F 2014. Identification of a common non-apoptotic cell death mechanism in hereditary retinal degeneration. PLoS One 9(11):e112142. PubMed

Kemmler R, Schultz K, Dedek K, Euler T, Schubert T. 2014. Differential regulation of cone calcium signals by different horizontal cell feedback mechanisms in the mouse retina. J Neurosci. 34, 11826-43. PubMed

Meyer A, Hilgen G, Dorgau B, Sammler EM, Weiler R, Monyer H, Dedek K, Hormuzdi SG. 2014. AII amacrine cells discriminate between heterocellular and homocellular locations when assembling connexin36-containing gap junctions. J Cell Sci. 127, 1190-202. PubMed 

Knop GC, Pottek M, Monyer H, Weiler R, Dedek K. 2014. Morphological and physiological properties of enhanced green fluorescent protein (EGFP)-expressing wide-field amacrine cells in the ChAT-EGFP mouse line. Eur J Neurosci. 39, 800-810. PubMed

2013

Ströh S, Sonntag S, Janssen-Bienhold U, Schultz K, Cimiotti K, Weiler R, Willecke K, Dedek K (2013) Cell-specific cre recombinase expression allows selective ablation of glutamate receptors from mouse horizontal cells. PLoS ONE 8(12): e83076. DOI: 10.1371/journal.pone.0083076. PubMed

 

Ahlers MT, Ammermüller J (2013) A system for precise temperature control of isolated nervous tissue under optical access: its application to multi electrode recordings. J Neurosci Methods 219:83-91. PubMed

Ahlers MT, Ammermüller J (2013) No influence of acute RF exposure (GSM-900, GSM-1800 and UMTS) on mouse retinal ganglion cell responses under constant temperature conditions. Bioelectromagnetics epub ahead: DOI: 10.1002/bem.21811. PubMed

Kranz K, Paquet-Durand F, Weiler R, Janssen-Bienhold U, Dedek K. 2013. Testing for a gap junction-mediated bystander effect in retinitis pigmentosa: secondary cone death is not altered by deletion of connexin36 from cones. PLoS One. 8,e57163. PubMed

Kranz K, Dorgau B, Pottek M, Herrling R, Schultz K, Bolte P, Monyer H, Penuela S, Laird DW, Dedek K, Weiler R, Janssen-Bienhold U. 2013. Expression of Pannexin1 in the outer plexiform layer of the mouse retina and physiological impact of its knock-out. J Comp Neurol. 521, 1119-1135. PubMed

2012


Hilgen G, Huebner AK, Tanimoto N, Sothilingam V, Seide C, Garrido MG, Schmidt KF, Seeliger MW, Löwel S, Weiler R, Hübner CA, Dedek K. 2012.
Lack of the sodium-driven chloride bicarbonate exchanger NCBE impairs visual function in the mouse retina. PLoS One. 7, e46155. PubMed


Sonntag S, Dedek K, Dorgau B, Schultz K, Schmidt KF, Cimiotti K, Weiler R, Löwel S, Willecke K, Janssen-Bienhold U. 2012. Ablation of retinal horizontal cells from adult mice leads to rod degeneration and remodeling in the outer retina. J Neurosci. 32, 10713-10724. PubMed

Kretschmer V, Kretschmer F, Ahlers MT, Ammermüller J. 2012. High speed coding for velocity by archerfish retinal ganglion cells. BMC Neurosci. 13, 69. PubMed

Landgraf I, Mühlhans J, Dedek K, Reim K, Brandstätter JH, Ammermüller J. 2012. The absence of Complexin 3 and Complexin 4 differentially impacts the ON and OFF pathways in mouse retina. Eur J Neurosci. 36, 2470-2481. PubMed

Cooper B, Hemmerlein M, Ammermüller J, Imig C, Reim K, Lipstein N, Kalla S, Kawabe H, Brose N, Brandstätter JH, Varoqueaux F. 2012. Munc13-independent vesicle priming at mouse photoreceptor ribbon synapses. J Neurosci. 32, 8040-8052. PubMed

Becker K, Jährling N, Saghafi S, Weiler R, Dodt HU. 2012. Chemical clearing and dehydration of GFP expressing mouse brains. PLoS.ONE. 7, e33916. PubMed

Kretschmer F, Ahlers MT, Ammermüller J, Kretzberg J. 2012. Automated measurement of spectral sensitivity of motion vision during optokinetic behavior. Neurocomputing 84:39-46.

2011

Pottek M, Knop GC, Weiler R, Dedek K. 2011. Electrophysiological characterization of GFP-expressing cell populations in the intact retina. J Vis Exp. 57, e3457. PubMed

Seeliger MW, Brombas A, Weiler R, Humphries P, Knop G, Tanimoto N, Müller F. 2011. Modulation of rod photoreceptor output by HCN1 channels is essential for regular mesopic cone vision. Nat Commun. 2, 532. PubMed

Klaassen LJ, Sun Z, Steijaert MN, Bolte P, Fahrenfort I, Sjoerdsma T, Klooster J, Claassen Y, Shields CR, Ten Eikelder HM, Janssen-Bienhold U, Zoidl G, McMahon DG, Kamermans M. 2011. Synaptic transmission from horizontal cells to cones is impaired by loss of connexin hemichannels. PLoS Biol. 7, e1001107. PubMed

Knop GC, Feigenspan A, Weiler R, Dedek K. 2011. Inputs underlying the ON-OFF light responses of type 2 wide-field amacrine cells in TH::GFP mice. J Neurosci. 31, 4780-4791. PubMed

 

Hilgen G, von Maltzahn J, Willecke K, Weiler R, Dedek K. 2011. Subcellular distribution of connexin45 in OFF bipolar cells of the mouse retina. J Comp Neurol. 519, 433-450. PubMed

2010

Frank M, Eiberger B, Janssen-Bienhold U, de Sevilla Müller LP, Tjarks A, Kim JS, Maschke S, Dobrowolski R, Sasse P, Weiler R, Fleischmann BK, Willecke K. 2011. Neuronal connexin-36 can functionally replace connexin-45 in mouse retina but not in the developing heart. J Cell Sci. 123, 3605-3615. PubMed

 

von Hauff E, Fuchs K, Hellmann DCh, Parisi J, Weiler R, Burkhardt C, Kraushaar U, Guenther E. 2010. Biocompatible molecularly imprinted polymers for the voltage regulated uptake and release of L-glutamate in neutral pH solutions. Biosens Bioelectron. 26, 596-601. PubMed

Müller LP, Dedek K, Janssen-Bienhold U, Meyer A, Kreuzberg MM, Lorenz S, Willecke K, Weiler R. 2010. Expression and modulation of connexin 30.2, a novel gap junction protein in the mouse retina. Vis Neurosci. 27, 91-101. PubMed

Feigenspan A, Dedek K, Schlich K, Weiler R, Thanos S. Expression and biophysical characterization of voltage-gated sodium channels in axons and growth cones of the regenerating optic nerve. 2010. Invest Ophthalmol Vis Sci. 51, 1789-99. PubMed

 

2009

 

Müller B, Glösmann M, Peichl L, Ammermüller J. 2009. Bat eyes have ultraviolet sensitive cone photoreceptors. PLoS One. 4, e6390. PubMed

 

Dedek K, Breuninger T, Pérez de Sevilla Müller L, Maxeiner S, Janssen-Bienhold U, Willecke K, Euler T, Weiler R. 2009. A novel type of interplexiform cell in the mouse retina. Eur J Neurosci. 30, 217-228. PubMed

Puller C, Pérez de Sevilla Müller L, Janssen-Bienhold U, Haverkamp S. 2009. ZO-1 and the spatial organization of gap junctions and glutamate receptors in the outer plexiform layer of the mammalian retina. J Neurosci. 29, 6266-6275. PubMed

 

Reim K, Regus-Leidig H, Ammermüller J, Radyushkin K, El Kordi A, Ehrenreich H, Brandstätter JH, Brose N. 2009. Aberrant Function and Structure of Retinal Ribbon Synapses in the Absence of Complexins 3 and 4. J Cell Sci. 122, 1352-1361. PubMed

Janssen-Bienhold U, Trümpler J, Hilgen G, Schultz K, Pérez de Sevilla Müller L, Sonntag S, Dedek K, Dirks P, Willecke K, Weiler R. 2009. Connexin57 is expressed in dendro-dendritic and axo-axonal gap junctions of mouse horizontal cells and its distribution is modulated by light. J Comp Neurol. 513, 363-374. PubMed

 

Ahlers MT, Bolz T, Bahr A, Ammermüller J. 2009. Temperature-controlled exposure systems for investigating possible changes of retinal ganglion cell activity in response to high-frequency electromagnetic fields. Radiat Environ Biophys. 48, 227-235. PubMed

Schweda F, Kurtz L, de Wit C, Janssen-Bienhold U, Kurtz A, Wagner C. 2009. Substitution of connexin40 with connexin45 prevents hyperreninemia and attenuates hypertension. Kidney Int. 75, 482-489. PubMed

Kurtz L, Janssen-Bienhold U, Kurtz A, Wagner C. 2009. Connexin expression in renin-producing cells. J Am Soc Nephrol. 20, 506-512. PubMed

Feigenspan A, Trümpler J, Dirks P, Weiler R. 2009. Ether-à-gogo-related gene (erg1) potassium channels shape the dark response of horizontal cells in the mammalian retina. Pflügers Arch. 458, 359-377. PubMed

 

Fuchs K, von Hauff E, Parisi J, Weiler R. 2009. Voltage regulated uptake and release of L-glutamate from a molecularly selective switch for physiological applications. Zeitschrift für Naturforschung 64a, 879–880.

 

2008

Trümpler J, Dedek K, Schubert T, de Sevilla Müller LP, Seeliger M, Humphries P, Biel M, Weiler R. 2008. Rod and cone contributions to horizontal cell light responses in the mouse retina. J Neurosci. 28, 6818-6825. PubMed

 

Dedek K, Pandarinath C, Alam NM, Wellershaus K, Schubert T, Willecke K, Prusky GT, Weiler R, Nirenberg S. 2008. Ganglion cell adaptability: does the coupling of horizontal cells play a role? PLoS One. 3, e1714. PubMed

Wellershaus K, Degen J, Deuchars J, Theis M, Charollais A, Caille D, Gauthier B, Janssen-Bienhold U, Sonntag S, Herrera P, Meda P, Willecke K. 2008. A new conditional mouse mutant reveals specific expression and functions of connexin36 in neurons and pancreatic beta-cells. Exp Cell Res. 314, 997-1012. PubMed

E. von Hauff, Yu. Meteleva-Fischer, J. Parisi, R. Weiler. 2008. Binding and release of glutamate from overoxidized polypyrrole via an applied potential for application as a molecular switch. Zeitschrift für Naturforschung A 63a, 359.

 

2007

Specht D, Tom Dieck S, Ammermüller J, Regus-Leidig H, Gundelfinger ED, Brandstätter JH. 2007. Structural and functional remodeling in the retina of a mouse with a photoreceptor synaptopathy: plasticity in the rod and degeneration in the cone system. Eur J Neurosci. 26, 2506-2515. PubMed

Pérez De Sevilla Müller L, Shelley J, Weiler R. 2007. Displaced amacrine cells of the mouse retina. J Comp Neurol. 505, 177-189. PubMed

 

Thiel A, Greschner M, Eurich CW, Ammermüller J, Kretzberg J. 2007. Contribution of individual retinal ganglion cell responses to velocity and acceleration encoding. J Neurophysiol. 98, 2285-2296. PubMed

2006

Dedek K, Schultz K, Pieper M, Dirks P, Maxeiner S, Willecke K, Weiler R, Janssen-Bienhold U. 2006. Localization of heterotypic gap junctions composed of connexin45 and connexin36 in the rod pathway of the mouse retina. Eur J Neurosci. 24, 1675-1686. PubMed

 

Urschel S, Höher T, Schubert T, Alev C, Söhl G, Wörsdörfer P, Asahara T, Dermietzel R, Weiler R, Willecke K. 2006. Protein kinase A-mediated phosphorylation of connexin36 in mouse retina results in decreased gap junctional communication between AII amacrine cells. J Biol Chem. 281, 33163-33171. PubMed

 

Greschner M, Thiel A, Kretzberg J, Ammermüller J. 2006. Complex spike-event pattern of transient ON-OFF retinal ganglion cells. J Neurophysiol. 96, 2845-2856. PubMed

Shelley J, Dedek K, Schubert T, Feigenspan A, Schultz K, Hombach S, Willecke K, Weiler R. 2006. Horizontal cell receptive fields are reduced in connexin57-deficient mice. Eur J Neurosci. 23, 3176-3186. PubMed

 

Schubert T, Weiler R, Feigenspan A. 2006. Intracellular calcium is regulated by different pathways in horizontal cells of the mouse retina. J Neurophysiol. 96, 1278-1292. PubMed

Thiel A, Greschner M, Ammermüller J. 2006. The temporal structure of transient ON/OFF ganglion cell responses and its relation to intra-retinal processing. J Comput Neurosci. 21, 131-151. PubMed

Döring B, Shynlova O, Tsui P, Eckardt D, Janssen-Bienhold U, Hofmann F, Feil S, Feil R, Lye SJ, Willecke K. 2006. Ablation of connexin43 in uterine smooth muscle cells of the mouse causes delayed parturition. J Cell Sci. 119, 1715-1722. PubMed

 

Kreuzberg MM, Schrickel JW, Ghanem A, Kim JS, Degen J, Janssen-Bienhold U, Lewalter T, Tiemann K, Willecke K. 2006. Connexin30.2 containing gap junction channels decelerate impulse propagation through the atrioventricular node. Proc Natl Acad Sci U S A. 103, 5959-5964. PubMed

Kharkovets T, Dedek K, Maier H, Schweizer M, Khimich D, Nouvian R, Vardanyan V, Leuwer R, Moser T, Jentsch TJ. 2006. Mice with altered KCNQ4 K+ channels implicate sensory outer hair cells in human progressive deafness. EMBO J. 25, 642-652. PubMed